Coenzyme Q10 (CoQ10) has fundamental and far reaching effects on health.’1
Unived uses a 100% natural, fermented, single bond, trans isomer Coenzyme Q10. This form of CoQ10 is bio-identical to the CoQ10 that is naturally produced within the body, hence it is the most bio-available form of CoQ10 in the market.
- Q-veg features a natural, fermented, single-bond, trans isomer of CoQ10.
- Each serving of Q-veg contains 10mg Piperine to increase the bio-availability of CoQ10, and 206mg of CoQ10.
- Q-veg is formulated for maximum bio-availability and bio-absorption – 98.2% or more .
- Q-veg is beneficial for cardiovascular health, energy and healthy ageing.
Q-veg is inspired by the unique and fundamental contribution of CoQ10 to heart health and overall energetics of the human body. CoQ10 is also called Ubiquinone due to its ubiquitous presence meaning that it is distributed across the body. It is found in most energy dependent organs including the hearth, kidney, liver, and muscles which require CoQ10 for optimum functioning. It is highly recommended for optimum energy and heart and muscular health.
Natural vs synthetic CoQ10
Supplementary CoQ10 is available in the natural or synthetic form. The two types have several distinguishing aspects:
Natural CoQ10 is obtained from a natural source that is, by the fermentation of natural yeast. Synthetic CoQ10 is manufactured in a two part process, where the one part ‘Co’ is chemically extracted from solanosol which is obtained from tobacco leaves; and, the other part ‘Q10’ is genetically made in a laboratory. These are then paired and called ‘CoQ10’ – however, this is not pure or bio-identical CoQ10. It may also contain impurities and exists in a crude form which is unlike the CoQ10 found naturally in the body.
The making of natural CoQ10 involves a single bond trans isomer CoQ10 whereas the synthetic production of CoQ10 leads to a double bond cis isomer CoQ10.
The differences in molecular structure are quite evident. As the body produces only single bond trans isomer CoQ10, the double bond cis isomer has poor absorption and not nearly as effective as naturally derived trans isomer CoQ10 used by Unived.
While the benefits of natural trans isomer CoQ10 are well documented, scientists have not yet determined whether the cis isomer form of CoQ10 confers the same protective benefits as naturally occurring trans CoQ10.
Bio-identical and bio-available
Any medication, when administered doesn’t directly get absorbed into the body. Its bioavailability depends upon several factors and is one of the essential tools of pharmacokinetics and must be considered when calculating dosages for non-intravenous routes of administration.
Since Unived’s Q-veg contains CoQ10 that is bio identical to the body’s own, it offers assured bioavailability and potency. To further strengthen its bioavailability and bio-efficacy, Q-veg contains 10mg Piperine (black pepper extract) an ingredient which is known for its bio-enhancing effect. Various drugs and nutrients are bio-enhanced by Piperine.
Therefore the overall impact of Q-veg is much more conducive to the body than is any synthetic form of CoQ10, ensuring maximum absorption (98.2%) into your body.
Therapeutic dosage & suggested use
Each Q-veg capsule contains 206mg of Coenzyme Q10 – with a 98.2% minimum bio-avalibality, you are ensured to get over 200mg with each serving – the daily recommended dose for adults.
Each Q-veg capsule contains 10mg Piperine for optimal bio-availability and bio-efficacy.
As a dietary supplement, adults take 1 capsule a day post meals or as directed by your physician.
What is CoQ10
Coenzyme Q10 or CoQ10 is also known as Ubiquinone and Ubidecarenone. It is a lipid molecule found in each of the 70 trillion cells of the human body. Widely distributed in nature, it is found in the mitochondria – the energy production hub of the cell.
The chief biochemical role of the coenzyme is to act as a key element in the electron transport chain – a series of redox reactions involved in the synthesis of Adenosine Triphosphate (ATP). A critically important macromolecule—arguably “second in importance only to DNA”—is ATP. It serves as the primary energy currency of the cell. The energy produced facilitates several cellular functions (virtually every activity of the cell). CoQ10 is essential for the health of nearly all human tissues and organs.
Nature properties and role
CoQ10 is a lipid (or fat) soluble molecule present mainly in the mitochondrial cell membrane. It is similar to vitamins in nature, though it is not addressed as such since it is endogenously produced within the body. The ‘Q’ in CoQ10 refers to the ‘benzoquinone‘ ring and ’10’ refers to the number of isoprenoid units it consists.
This nutrient plays a unique role by transporting electron and protons, supporting ATP (cellular energy) synthesis in the mitochondrial inner membrane. By stabilizing the cell membranes, it preserves cellular integrity and function. CoQ10 is a powerful and versatile antioxidant that blocks oxidative injuries to DNA, lipids, proteins, and other essential molecules.
Coenzyme Q10 also plays a role as an antioxidant. Being involved in the intricate oxidation reduction cycle of energy production, it easily loses electrons, acting as an antioxidant. As a result, it prevents and protects the lipids and proteins from oxidation.
Vitamin E another important antioxidant is regenerated with the help of Coenzyme Q10. Due to its ability to neutralize toxins and free radicals, CoQ10 finds applicability as an essential nutrient for various health concerns such as heart disease, periodontal disease, immune disorders and neurodegenerative diseases.
Although this nutrient can be synthesized naturally by the body, there are several instances when the body falls short of synthesizing enough to meet its energy requirements. The metabolically active cells such as those in the heart, immune system, gingival and gastric mucosa are most likely to suffer from deficiency since they have the highest CoQ10 requirements. Deficient levels are observed in a wide range of medical conditions, including cardiovascular disease, hypertension, periodontal disease, and AIDS.
Experts point out a combination of elements including reduced biosynthesis, increased utilization and lack of dietary intake as factors responsible for depletion. The biosynthesis of CoQ10 is an elaborate 17-step process, ﬁrst described by Folkers that requires the availability of several vitamins or their coenzyme forms: vitamins B2, B6, B12, C, folic acid, niacinamide, pantothenic acid, as well as many trace elements. A deficiency in any of these nutrients can impact the synthesis of CoQ10.
CoQ10 levels are also affected by advancing age and declining levels in turn impact the manifestations of aging. The role of cholesterol loweing drugs in lowering CoQ10 levels, along with the cholesterol which they are actually meant for, has been under scrutiny since over a decade. The induced deficiency caused by cholesterol lowering drugs can have grave implications including heart failure. Other drugs that impact CoQ10 levels include blood sugar and pressure lowering drugs.
Coenzyme Q10, with its beneficial effects on cellular bioenergetics, regulation of cell membrane pathways and its antioxidant properties, has emerged as a critical adjuvant therapy. It can tone down other pharmacological treatments, improve quality of life and decrease occurrence of complications. Coenzyme Q10 is possibly ushering a new era of cellular/biochemical treatment, as a complementary approach for treating several disorders, especially cardiovascular treatment.
Unived’s Q-veg is CoQ10, in its most natural and pure form. It is formulated so that you may experience the maximum benefits of this multifarious nutrient.
CoQ10 is often referred to as the miracle nutrient. Medical practitioners around the world subscribe to the use of this nutrient for several reasons. According to renowned cardiologist Dr. Stephen Sinatra, ‘I wouldn’t practice cardiology without Coenzyme Q10. If there is just one thing you do to help maintain your heart’s health, make sure you’re taking CoQ10 daily’.
Q-veg facilitates all energy dependent processes of the body, including heart muscle contraction. At the same time, the overall significance of CoQ10 supplementation for your heart is undeniable.
- CoQ10 is useful in arteriosclerosis, ischemic heart disease, chronic heart failure (for both systolic and diastolic heart failure), cardiomyopathy, cardiovascular surgery, hypertension, arrhythmias, valvular heart diseases as well as toxin-induced cardiomyopathy.
- Heart treatment over the years has indicated the role of inflammatory mediators in the development of congestive heart failure and acute myocardial infarction. In a recent study, the administration of CoQ10 significantly attenuated the increase of oxidative and nitrative stress markers and inﬂammatory markers in a dose-dependent manner.
- Research and trials show the effectiveness of CoQ10 administration in impacting heart failure and heart transplant candidates. Significant improvement has been observed in functional status, clinical symptoms, and quality of life. CoQ10 can restore heart function even in highly precarious heart conditions.
- Clearly, the heart is highly sensitive to CoQ10 deficiency. The reduced energy reserve in heart failure cases may be considered to contribute to the progression of the disease.
Unived’s Q-veg, with bio-identical pure CoQ10, provides energy for your heart muscles and functioning and can play an important role in prevention and treatment of cardiovascular disease.
Several factors including advancing age, drugs’ side effects and insufficient biosynthesis bring a decline in the body’s CoQ10 levels. Hence an external supply of CoQ10 becomes essential.
- CoQ10 is mostly found in limited non-vegetarian sources such as pork, heart, beef and fish. Vegetarians cannot get enough CoQ10 unless they eat large quantities of peanuts (17 pounds) and/or broccoli (206 cups). The average person only gets 2–5mg CoQ10 a day from diet.
- Soybean oil, canola oil, peanuts, sesame seeds, broccoli, cauliflower, strawberries and pistachios also have varying amounts of CoQ10. However, dietary sources of the enzyme are not enough to have a significant impact on heart failure.
- Q-veg is a pure, natural and 100% vegetarian & vegan product. It is identical to the body’s own CoQ10 and easily gets absorbed in the body. Piperine (10mg) is also added to the formulation for enhanced bio-availability.
Young adults and working professionals
As young adults and working professionals, you live in challenging conditions and juggle multiple dimensions of life. When energy, strength and stamina become your primary concern, Q-veg is your reliable natural source of energy and so much more. For Q-veg addresses a variety of lifestyle related health problems.
Energy and stamina
‘Energy has been called the currency of life and the implications are profound when you consider that every one of the body’s 70 trillion cells depends on CoQ10 for energy production.'
- CoQ10 plays a key role in ATP energy production. ATP is the chemical energy that propels several cellular functions in the body. Without CoQ10 the body is not able to produce ATP.
- Deficient CoQ10 levels can have severe consequences including fatigue. A study on the effect of CoQ10 on sedentary individuals concludes that CoQ10 improves physical performance in sedentary individuals.
- A study found that trained and untrained men and women had greater endurance after taking 200mg of CoQ10 for two weeks.
23.10% men and 22.60% women above 25 years suffer from hypertension in India. Practitioners are expressing concern about the prevalence as well as the number of hypertension cases that go undetected. As per the World Health Organization (WHO), high blood pressure affects every third person above the age of 18.
- Those suffering from hypertension in the long term may encounter problems with their vision (hypertensive retinopathy) and reduced blood supply to your legs.
- Several studies reveal CoQ10 deficiency in the patients suffering from hypertension. Treatment with CoQ10 decreases blood pressure in patients with essential hypertension. It seems to correct some abnormality involved in the pathogenesis of hypertension.
CoQ10 is also seen to be particularly effective in hypertension in diabetics and not only lowers blood pressure but also improves diabetic control perhaps by improving insulin resistance.
- Since it is a component of the electron transport chain, CoQ10 is significant for carbohydrate metabolism. Depletion of CoQ10 levels might have an adverse effect on glucose tolerance.
- Long-term CoQ10 addition in doses of 150mg daily may enhance insulin secretion and prevent progressive hearing loss in these patients with mitochondrial diabetes.
- Periodontal disease affects about 60% of young adults and 90% of the individuals over the age of 65 years. Healing and repair of periodontal tissues requires energy production.
- Gum disease is a common problem that causes swelling, bleeding, pain, and redness of the gums. Clinical studies show that people with gum disease tend to have low levels of CoQ10 in their gums.
- In a trial it was found that CoQ10 intake of 50mg/day for 21days significantly improved clinical aspects of periodontal disease such as inflammation, pocket depth and tooth mobility.
As it is involved in energy production, CoQ10 can enhance aerobic capacity and muscle performance.
- In a study for determining the impact of CoQ10 supplementation on exercise-induced muscular injury and oxidative stress in kendo athletes during training, researchers concluded that CoQ10 supplementation is useful for reducing muscular injury in athletes.
- In another study, researchers reported that people were able to cycle faster and achieved quicker recovery times after just one week of taking regulated CoQ10 doses, daily.
- In absence of external sources, Coenzyme Q10 levels may decrease by 50%. Exercise also decreases circulating Q10 plasma levels observed in runners immediately following exercise.
- Supplemental Coenzyme Q10 dose increases plasma levels, reduces muscle cell oxidant damages, and increases energy metabolism rebound for future exercise demand.
- Researchers reported endurance of athletes supplementing CoQ10 who have higher muscle concentrations, and lower serum oxidative stress after exercise, resulting in increased exercise time to exhaustion.
- Without enough CoQ10, deficiency is predicted in an endurance athlete, resulting in suboptimal levels during peak exercise states.
Q-veg offers the world’s most reliable CoQ10 for improving your overall health and performance. Each serving provides 206mg, of energy and stamina boosting CoQ10 that fits perfectly well into an athlete’s lifestyle.
Cholesterol lowering drug users
Cholesterol lowering drugs are popularly prescribed for treating high cholesterol. The objective is to address the morbidity and mortality consequent to cardiovascular problems primarily by treating elevated cholesterol levels. However since cholesterol and CoQ10 partially share their biosynthetic pathway, while blocking cholesterol biosynthesis cholesterol lowering drugs also block CoQ10 biosynthesis. The consequences of which are harmful to say the least. With Q-veg you can replenish your CoQ10 levels and ensure that you stay healthy.
- Several human trials evaluating the effect of cholesterol lowering drug therapy, have frequently reported significant depletion in blood CoQ10 levels, particularly when cholesterol lowering drugs are taken at higher doses and most notably in the elderly.
- It is likely that the beneﬁcial hypo-cholesterolemic effect of lipophylic cholesterol lowering drugs may be negated by the adverse effects of the inhibition of the mitochondrial energy-generating system.
- Cholesterol lowering drugs inﬂuence a wide range of physiological functions, such as vasodilative, antithrombotic, antioxidant, anti-proliferative, anti-inflammatory, and even immunosuppressive, anticoagulant, and bone-formation-inducing capabilities.
- Patients undergoing bypass surgery may be more susceptible to cholesterol lowering drug-induced lowering of Coenzyme Q10 cardiac tissue levels.
- Every year, approximately 1.5 million people on cholesterol lowering drug therapy are likely to develop muscle-related complications directly related to cholesterol lowering drug use. These adverse events also referred to as cholesterol lowering drugs-induced myopathy, manifest as myalgia, myositis, or rhabdomyolysis.
- After its association with around 100 rhabdomyolysis-related deaths, a cholesterol lowering drug was removed from the global market in 2001.
- All prescribing physicians should be notified that cholesterol lowering drugs produce depletion in Coenzyme Q10 and if CoQ10 deficiency is already present, in case of heart failure patients or aged individuals then the myocardial function may get worse.
- Since it is not possible to obtain CoQ10 from daily dietary sources enough to bolster reducing levels of cholesterol lowering drug-induced CoQ10 deficiencies, the intake needs to be in specific supplement form and within 100-200mg.
Your physiological systems become rather vulnerable as you age which put you at higher probability of suffering from an ailments.
- CoQ10 levels steadily fall after the age of 40.
- Most aged people fall prey to non-communicable diseases such as heart disease, cancer and diabetes, rather than from infectious and parasitic diseases. Older people also often have health problems at the same time, such as diabetes and heart disease.
- An age-dependent decline of CoQ10 levels is indicated as a factor responsible for the diseases of aging.
- CoQ10’s antioxidant properties contribute to prevention of lipid peroxidation. It has been found to be efficient in preventing LDL oxidation which is an important step in evolution of atherosclerosis.
- Elderly patients who are on cholesterol lowering drug therapy would greatly benefit from supplemental CoQ10.
- Patients with Parkinson’s Disease have low levels of CoQ10, which are a major source of free radicals within the cell.
- Studies have demonstrated immune-enhancing effects of Coenzyme Q10.
- CoQ10 may have potential as an agent for life extension by retarding the accelerated death of cells involved in the aging process.
Unived’s Q-veg with its powerful antioxidant action protects you from cellular degeneration and supports overall heart and muscular health. It supports your immunity, adds vigor and helps stabilize your vital statistics.
What is CoQ10 or Coenzyme Q10?
CoQ10 or Coenzyme Q10 is a fat (or lipid) soluble substance found naturally, in every cell of the human body. It is also known as Ubiquinone or Ubidecarenone. It has similar properties to vitamins except that it is synthesized within the body. As part of the electron transport chain it acts as a carrier of electrons and protons, contributing to the making of cellular energy within each cell. This cell is known as Adenosine triphosphate or ATP. Basically, without CoQ10, our body will not be able to make any energy that is requisite for carrying out all the vital functions of the body. CoQ10 is widely acknowledged for its protective effect on cardiovascular health. It strengthens the heart muscles, provides energy and can also prevent heart attacks and strokes.
Where does CoQ10 occur in nature?
CoQ10 is mostly found in non-vegetarian sources such as beef, heart, pork, chicken livers, and fish (especially salmon, mackerel and sardines). Peanuts, broccoli, spinach and soybean oil are the vegetarian sources. However, to acquire the requisite daily quantum of CoQ10, you will need to consume enormous quantities of these foods for instance you will need to consume 206 cups of broccoli, 17 pounds of peanuts, 14 pounds of beef or 7 pounds of sardines to consume the required the amounts of CoQ10 through your diet.
Why do I need Q-veg when CoQ10 is already produced within the body?
It is true that the body is capable of producing its own CoQ10. However, there are several factors that contribute to the decline in its levels and then the body is unable to fulfill its daily requirement. The depletion of CoQ10 invariably takes place as you gain years. Ageing is one of the main factors that lead to CoQ10 depletion. Inadequate biosynthesis and dietary intake are other factors that lead to CoQ10 deficiency. Since the making of CoQ10 involves a complex process and requires several nutrients too, a deficiency even in a single element can falter the process. Dietary intake can never supply your body with adequate CoQ10 levels. That is why it is necessary to take CoQ10 supplements, especially when you consider the ill effects of CoQ10 deficiency including weak heart, fatigue and stroke. It also affects the vital organs of your body such as heart, liver, kidney etc. since they are highly energy dependent upon CoQ10.
What are the types of CoQ10 supplements available in the market?
CoQ10 is usually available in two types, synthetic and natural. The natural type of CoQ10 consists of trans isomer Whereas the synthetic type of CoQo10 consists of the cis isomer – a crude form. The natural CoQ10 is derived from natural yeast fermentation and is identical to the CoQ10 found naturally in humans. The synthetic type is produced chemically, from bacteria or tobacco and it varies in its structure from the natural CoQ10. Whereas the natural type of CoQ10 supplements show proven benefits, the impact of synthetic CoQ10 is not documented.
How is Q-veg any different from other CoQ10 Supplements?
Q-veg is 100% natural and vegetarian. As it is bio-identical to the CoQ10 in the body, it acts an effective supplement restoring to the body, its energy and health. Q-veg uses a fermented and natural form of CoQ10. It is free from any impurities, GMO and allergens. Q-veg also contains Piperine extract (10 mg) to enhance its bioavailability.
Is it suitable for Vegans?
Yes. Q-veg is suitable for vegans as well as Jains. It is derived from a 100% natural vegetarian source, fermented natural yeast. Dietary sources of CoQ10 are limited and more so for vegans, since it is mostly found in non-vegetarian sources like organ meats. The vegetarian sources too are few, which include broccoli, peanuts and soybean oil.
Who can use Q-veg?
Q-veg finds applicability in a wide spectrum of people since it is useful for a wide range of disorders. Q-veg is extremely useful for those suffering from heart trouble, diabetes, blood pressure or hypertension and high cholesterol. It is expressly important for cholesterol lowering drug users since these drugs are responsible for inhibiting the production of CoQ10 in the body, as a side effect. Q-veg is also very useful for all ageing individuals in general since advancing age causes CoQ10 levels to deplete. Supplementation with Q-veg is hence extremely important.
Q-veg is also used by athletes for its energy enhancing effect. Q-veg can improve their energy and stamina and can also prevent muscle loss in case of injury.
Is Q-veg free of allergens and GMOs?
Q-veg offers a fermented form of CoQ10 that is completely devoid of GMO and allergens. Individuals allergic to or with intolerance to yeast or yeast derivatives should consult a healthcare provider before taking this supplement.
Is Q-veg safe for long term use?
Q-veg is safe for both long term, as well as short term use and has no reported side-effects. Consult your licensed healthcare provider before you start taking CoQ10 supplements, especially if you have been diagnosed with a heart condition.
Does Q-veg have any drug interactions?
Q-veg is safe and devoid of any known drug interactions. However, in case you are consuming any OTC or prescription medication, it is best to consult your licensed healthcare provider.
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