Unived’s PCOS Management Plus is formulated to help in moderate to severe symptoms of PCOS. It contains 4gm of Myo-Inositol and 100mg of Caronositol® which is a natural Plant-Based D-Chiro-Inositol in the clinically researched 40:1 ratio, which match the body’s idea physiological ratio.
Myo-Inositol – it is naturally converted to DCI in the body but because of epimerase inactivity it is excess in the serum and due to DCI-paradox deficient in the ovaries. Thus is important to supplement with both the inositols to achieve balance. MI has shown to lower LH, PRL, T and insulin levels significantly, as well as LH/FSH ratio and insulin resistance to some extent.
Caronositol® – unived’s PCOS contains natural D-Chiro-Inositol from carob extract which helps with ovulation by maintaining serum progesterone levels, reducing LH/FSH ratio and LH levels also reduces insulin resistance and hyperandrogenism (free testosterone).
ALA – is an absolute antioxidant that reduces oxidative stress. It is reported to help with improving ovulation, number of menses, serum progesterone levels and reduction of number of ovarian peripheral cysts. Also helps reduce insulin resistance and insulin levels and increases HDL-C
Chromium picolinate – works as an auto amplification system for insulin Signaling and helps reduce fasting blood glucose levels thus aiding the enhancement of insulin sensitivity. It also helps with reducing testosterone levels.
Vitamin D3 – is natural and plant-based and helps with reduction of insulin resistance and excessive androgen (male hormone) levels, also helps deal with menstrual dysregulation and improves follicular responses to FSH hormone and normalizes AMH levels.
Calcium – it is very important for regular menstrual cycles as it plays a role in activation of oocytes and improving follicular responses also helps to lower LH levels and increase levels of FSH.
Zinc – Zinc supplementation has beneficial effect in regulating hormonal balance, glucose metabolism, lipid metabolism, reducing oxidative stress and inflammation.
Every ingredient plays a part in normalizing one or all hormones that are involved in PCOS. The basic goal is to lower LH, insulin, insulin resistance, androgens and improve FSH responses. All this together will promote ovulation and regular menstrual cycles.