Caffeine and L-theanine synergize to optimize athletic performance and are proven to improve cognition to a greater extent when taken together in the proven 1:2 ratio.
Vitamins B12, B9 and B6 combine to help you stay focused, and extend short & long-term alertness.
Unlike traditional caffeine capsules or energy drinks – you will not experience a crash with this product.
• Steady and focused energy
• Focus & clarity of mind
• Improved reaction time
• Positive mood and overall relaxation
• Reduced stress
• No crash
• No jitters
Caffeine & L-Theanine Synergy
Caffeine + L-Theanine have synergistic effects on cognition – meaning that together they produce cognitive benefits not seen when either is used alone. The specific ratio of 1:2 of caffeine to L-Theanine in Nootro-Peak matches the dosage widely shown in clinical trials to produce optimal performance gains. In clinical trials the 1:2 ratio of Caffeine to L-Theanine has been proven to:
- Increase Sustained Attention by 13.94%: sustained attention is calculated by testing a variance of cognitive variables including, digit vigilance, digit accuracy and digit false alarms(12)
- Increase Semantic Memory by 3.34%: semantic memory is calculated by testing cognitive variables such as word recognition, word recognition reaction time and delayed word recall (12)
- Increase Simple Reaction time by 9.27%: controlled clinical testings have shown significant increases in simple reaction time (tested by capturing the time taken to react to a screen by pressing a button) (12)
- Increase Self Reported Alertness by 19.49%: throughout multiple studies conducted, patients reported increased alertness 1 hour after after ingestion of Caffeine + L-Theanine (12)
L-Theanine is an amino acid analog of glutamate and glutamine found in green tea from Camellia sinensis with neuroprotective effects. L-Theanine has anxiolytic activity and is clinically proven to have favorable effects on reducing stress & anxiety, as well as reduce blood pressure and cerebral vascular restriction caused by caffeine intake.
- Increases alpha brain waves – promotes attention and relaxation without sedation
- Synergistic with caffeine in promoting concentration, motivation and memory
- Can modulate the release of Dopamine, improving mood
- Antioxidant effects and protects neurons from damage and hypoxia
- May upregulate the production of proteins associated with neuronal growth
- Works by reducing your stress levels so you can think clearer and stay calmer throughout the day
Caffeine is a methylxanthine found in tea. Caffeine is clinically proven as a brain stimulant that increases alertness, wakefulness, attention, working memory, and motor activity.
- It increases alertness and is brain stimulator
- It helps to increase performance and reduces time to exertion by providing energy
- Increases motor activity through inhibition of acetyl cholinesterase
- Increases cortical activation in the brain
- Increases information processing rate and concentration
- Increases cerebral metabolism
VITAMIN B12 as Methylcobalamin (99%)
Methylcobalamin is a methylated and active form of Vitamin B12 (cobalamin) with strong neuroprotective and anti-aging effects. Methylcobalamin’s effects include improved memory and executive function, as well as enhanced focus.
Vitamin B12 is essential for generating new red blood cells, maintaining neurologic function, and DNA synthesis.
- Acts as a cofactor for a number of enzymes and provides functional support for neurons
- Improves neuronal regenerative capacity and reduces neurotoxicity
- Can decrease neuropathy and neuropathic pain
- Removes excessive homocysteine in the brain – main cause of vascular degeneration
- Upregulates S-adenosylmethionine production – antidepressant effect
- Improves memory, concentration, executive function, and motor control
- Prevents age-associated cognitive decline
VITAMIN B6 as Pyridoxal 5 Phosphate
Pyridoxal 5 Phosphate (P-5-P) is the most active form of Vitamin B6. P-5-P plays an essential part in mood, memory formation, and executive functions.
- Essential for cellular energy metabolism
- Increases mental and physical energy, improves neuronal communication.
- Prevents age-associated neuronal damage
- Involved in the synthesis of acetylcholine, dopamine, serotonin, noradrenaline and melatonin.
- Important role in executive functions, memory formation, mood regulation, focus, motivation, and sleep regulation
VITAMIN B9 as Methyltetrahydrofolate (5-MTHF)
5-MTHF is the most active form of Vitamin B9 and is critical in optimizing brain functionality.
- Folate is involved in DNA and RNA synthesis and gene expression
- Folate is required for the synthesis of dopamine, epinephrine and serotonin
- Folate’s involvement in neurotransmitter synthesis is most responsible for mood and cognition
1. Deijen, J. B., van der Beek, E. J., Orlebeke, J. F., & van den Berg, H. (1992). Vitamin B-6 supplementation in elderly men: effects on mood, memory, performance and mental effort. Psychopharmacology (Berl), 109(4), 489-496.
2. Bryan, J., Calvaresi, E., & Hughes, D. (2002). Short-term folate, vitamin B-12 or vitamin B-6 supplementation slightly affects memory performance but not mood in women of various ages. J Nutr, 132(6), 1345-1356.
3.Schneider, Z., & Stroinski, A. (1987). Comprehensive B12: chemistry, biochemistry, nutrition, ecology, medicine: Walter de Gruyter.
4. Dodd, F. L., Kennedy, D. O., Riby, L. M., & Haskell-Ramsay, C. F. (2015a). A double-blind, placebo-controlled study evaluating the effects of caffeine and L-theanine both alone and in combination on cerebral blood flow, cognition and mood. Psychopharmacology (Berl), 232(14), 2563-2576. doi:10.1007/s00213-015-3895-015.
5. Rogers, P. J., Smith, J. E., Heatherley, S. V., & Pleydell-Pearce, C. W. (2008). Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together. Psychopharmacology (Berl), 195(4), 569-577. doi:10.1007/s00213-007-0938-116.
6. Foxe, J. J., Morie, K. P., Laud, P. J., Rowson, M. J., de Bruin, E. A., & Kelly, S. P. (2012). Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task. Neuropharmacology, 62(7), 2320-2327. doi:10.1016/j.neuropharm.2012.01.02017.
7. Giesbrecht, T., Rycroft, J. A., Rowson, M. J., & De Bruin, E. A. (2010). The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness. Nutr Neurosci, 13(6), 283-290. doi:10.1179/147683010×1261146076484018.
8. Haskell, C. F., Kennedy, D. O., Milne, A. L., Wesnes, K. A., & Scholey, A. B. (2008). The effects of L-theanine, caffeine and their combination on cognition and mood. Biol Psychol, 77(2), 113-122. doi:10.1016/j.biopsycho.2007.09.00819.
9. Kahathuduwa, C. N., Dassanayake, T. L., Amarakoon, A. M., & Weerasinghe, V. S. (2016). Acute effects of theanine, caffeine and theanine-caffeine combination on attention. Nutr Neurosci. doi:10.1080/1028415x.2016.114484520.
10. Owen, G. N., Parnell, H., De Bruin, E. A., & Rycroft, J. A. (2008). The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutr Neurosci, 11(4), 193-198. doi:10.1179/147683008×30151321.
11. Einother, S. J., Martens, V. E., Rycroft, J. A., & De Bruin, E. A. (2010). L-theanine and caffeine improve task switching but not intersensory attention or subjective alertness. Appetite, 54(2), 406-409. doi:10.1016/j.appet.2010.01.003
12. Haskell, C. F., Kennedy, D. O., Milne, A. L., Wesnes, K. A., & Scholey, A. B. (2008). The effects of L-theanine, caffeine and their combination on cognition and mood. Biol Psychol, 77(2), 113-122. doi:10.1016/j.biopsycho.2007.09.008